You’ve tried the creams. You’ve done the lasers. You’ve been patient — and still, every summer, the patches come back. Here’s the truth: you haven’t been treating it wrong. You may simply have been treating the wrong layer.
“Melasma is not just a pigment problem — it is a sign that the skin itself is aging from the inside out.”
— Passeron & Picardo, Pigment Cell Melanoma Research, 2018
What Science Has Recently Uncovered
Leading research from Europe and Asia over the past decade has confirmed that melasma is far more than excess pigment. It is now understood as a photoaging skin disorder — a condition where cumulative sun damage reshapes the skin’s structure at every layer, from the outermost epidermis down to the deep dermis.
Skin affected by melasma shows measurable changes: increased capillaries, a disrupted skin barrier — and most critically — prematurely aged cells deep within the dermis.
The Hidden Root in the Dermis
How Melasma Really Forms
Did You Know? Melasma Is Also Triggered By…
- Blue-violet light from screens and sunlight — which ordinary sunscreen does not adequately block
- Capillaries in melasma-prone areas that release Endothelin-1, a compound that deepens pigmentation
- Sebaceous glands on the cheeks, forehead and upper lip that send additional signals to melanocytes
This is precisely why some people find that laser treatments make their melasma darker — when only the surface pigment is targeted without addressing the aged dermis beneath, senescent cells simply restimulate the pigment faster than before.
A New Approach: Three Levels, Treated Together
Leading dermatologists worldwide are shifting their thinking — from treating pigment alone, to caring for the entire skin ecosystem.
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Pillar 3 is what conventional treatments have always missed — clearing the senescent cells and rebuilding a skin environment that no longer sends the signal to produce more pigment.
Treatment at Piyawat Clinic
Built on the concept of “Melasma as a Skin Ecosystem Disease,” our physicians design programs tailored to each person’s actual level of skin deterioration.
The right program is determined through a thorough skin assessment by our physicians, ensuring precise, safe results tailored to you.
Ready to Treat Melasma at Its Root?
Begin with a personalised skin assessment with our specialist physicians — and build a treatment plan that truly matches your skin.